# MHRA Yellow Card iDAP

This provider exposes tools and data accessible through its parent verticals. Use the example prompts as inspiration for your queries.

**Slug:** `mhraidap`

**Description:** Search MHRA Yellow Card interactive Drug Analysis Profiles and read UK spontaneous suspected adverse drug reaction data for a substance: reaction counts at any MedDRA level (System Organ Class, High-Level Group Term, High-Level Term, Preferred Term) with serious and fatal breakdowns, a disproportionality screen (ROR, PRR) against all UK reports, and a case-level profile by sex, age, year, reporter and route. UK cases are held here rather than in EudraVigilance since Brexit.

## Verticals

This provider is available in the following verticals:

- [Medical](https://kirha.com/verticals/medical.md)

## Example prompts (non-exhaustive)

- `How many UK adverse reaction reports are there for paracetamol?`
- `Break down semaglutide UK adverse reactions by MedDRA system organ class`
- `Which preferred terms sit inside Eye disorders for warfarin in the UK?`
- `Break down ibuprofen UK adverse reaction reports by age band`
- `How many fatal UK reports are there for methotrexate?`
- `Is any MedDRA group disproportionately reported for methotrexate in the UK Yellow Card data?`
- `Find the MHRA iDAP entry for atorvastatin`

## Available tools in this provider

Open a tool to see its input and output schemas.

### [`searchSubstances`](https://kirha.com/providers/mhraidap/searchSubstances.md)

Search MHRA Yellow Card iDAP substances (UK medicines and vaccines) by name. Use a returned substanceName with getSubstanceReactions, getSubstanceCases or getSubstanceReactionDisproportionality.

### [`getSubstanceReactionDisproportionality`](https://kirha.com/providers/mhraidap/getSubstanceReactionDisproportionality.md)

Disproportionality screen (ROR, PRR) over UK MHRA Yellow Card iDAP for one substance, at a MedDRA level. UK counterpart of the EudraVigilance and FAERS screens, computed only against Yellow Card denominators. Resolve the substance name with searchSubstances first.

### [`getSubstanceCases`](https://kirha.com/providers/mhraidap/getSubstanceCases.md)

UK case-level reporting profile for one substance from MHRA Yellow Card iDAP: totals and demographic, seriousness, reporter and route breakdowns. Resolve the substance name with searchSubstances first.

### [`getSubstanceReactions`](https://kirha.com/providers/mhraidap/getSubstanceReactions.md)

UK adverse reaction counts for one substance from MHRA Yellow Card iDAP, grouped at a MedDRA level, with drill-down into a broader term. Resolve the substance name with searchSubstances first.

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**Tags:** pharmacovigilance, adverse-reactions, pharma, mhra, healthcare, regulatory, uk

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