# getDrugIndications

**Identifier:** `chembl_getDrugIndications`

**Provider:** [ChEMBL](https://kirha.com/providers/chembl.md)

Drug indications from ChEMBL with the max clinical phase reached for each (4 = approved), mapped to EFO and MeSH, with supporting NCT IDs and label references. Salts are resolved to the parent compound. diseaseId uses the Open Targets format (EFO_0000339) for opentargets-mcp getDiseaseAssociatedTargets/getKnownDrugs; NCT IDs feed clinicaltrials-mcp getStudyDetails.

## Run it with the CLI

```bash
kirha tools run chembl_getDrugIndications \
  --input '{
    "chemblId": "CHEMBL941"
  }'
```

`--input` takes a JSON object that matches the input schema. Pass `--input -` to read it from stdin.

## Call it over HTTP

```bash
curl https://api.kirha.com/tools/v1/execute \
  --request POST \
  --header 'Content-Type: application/json' \
  --header 'Authorization: **********' \
  --data '{
  "tool_name": "chembl_getDrugIndications",
  "input": {
    "chemblId": "CHEMBL941"
  }
}'
```

Replace the stars with an API key from https://app.kirha.com/api-keys.

## Input schema

```json
{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "properties": {
    "chemblId": {
      "description": "e.g. CHEMBL941, from searchMolecules",
      "pattern": "^CHEMBL\\d+$",
      "type": "string"
    },
    "minPhase": {
      "default": 0,
      "description": "4 = approved only, 3 = phase 3 or later",
      "maximum": 4,
      "minimum": 0,
      "type": "number"
    }
  },
  "required": [
    "chemblId"
  ],
  "type": "object"
}
```

## Output schema

```json
{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "additionalProperties": false,
  "properties": {
    "chemblId": {
      "description": "Parent ChEMBL ID",
      "type": "string"
    },
    "context": {
      "type": "string"
    },
    "indicationCount": {
      "type": "number"
    },
    "indications": {
      "items": {
        "additionalProperties": false,
        "properties": {
          "diseaseId": {
            "description": "EFO/MONDO ID as recorded by ChEMBL; some are obsolete in Open Targets, resolve the name with searchEntities then",
            "type": "string"
          },
          "indication": {
            "type": "string"
          },
          "maxPhase": {
            "type": "number"
          },
          "meshHeading": {
            "type": "string"
          },
          "meshId": {
            "type": "string"
          },
          "nctIds": {
            "items": {
              "type": "string"
            },
            "type": "array"
          },
          "otherReferences": {
            "description": "Label sources, e.g. FDA, EMA, DailyMed, ATC",
            "items": {
              "type": "string"
            },
            "type": "array"
          }
        },
        "required": [
          "indication"
        ],
        "type": "object"
      },
      "type": "array"
    },
    "maxPhase": {
      "description": "Highest phase across all indications",
      "type": "number"
    },
    "name": {
      "type": "string"
    },
    "nctIds": {
      "description": "NCT IDs across indications, for clinicaltrials-mcp getStudyDetails",
      "items": {
        "type": "string"
      },
      "type": "array"
    }
  },
  "required": [
    "context",
    "chemblId",
    "indicationCount",
    "indications",
    "nctIds"
  ],
  "type": "object"
}
```

## Related tools

Other ChEMBL tools that this tool refers to, or that refer to it.

- [`searchMolecules`](https://kirha.com/providers/chembl/searchMolecules.md)

-----

[All ChEMBL tools](https://kirha.com/providers/chembl.md) · [< Back to tools list](https://kirha.com/tools.md)